Congenital Syphilis

Congenital syphilis is a transplacental fetal infection with T.pallidum 

Symptoms & Signs: 

Early symptoms (within 2 years of life): flu-like syndrome associated with nasal discharge (snuffles), maculopapular rash, anemia, jaundice, hepatosplenomegaly,hydrocephalus, lymphadenopathy, chorioretinitis 

Late symptoms (after 2 years of life): Saddle nose, saber shins, short maxilla, frontal bossing, high palatal arch, eighth nerve deafness, interstitial keratitis, triangular or peglike teeth (Hutchinson teeth)

-The most common eye lesion in congenital syphilis: interstitial keratitis

-treatment of the mother during pregnancy prevents congenital syphilis 

-All infants born to mothers with positive syphilis tests should have RPR or VDRL test 

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